Fa-Jun NAN: search on Z-Library

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1

High-throughput screening using pseudotyped lentiviral particles: A strategy for the identification of HIV-1 inhibitors in a cell-based assay

Jean-Michel Garcia, Anhui Gao, Pei-Lan He, Joyce Choi, Wei Tang, Roberto Bruzzone, Olivier Schwartz, Hugo Naya, Fa-Jun Nan, Jia Li, Ralf Altmeyer, Jian-Ping Zuo

Journal:

Antiviral Research

Year:

2009

Language:

english

File:

PDF, 1.12 MB

english, 2009

2

Modulation of the G-Protein-Coupled Receptor 84 (GPR84) by Agonists and Antagonists

Chen, Lin-Hai, Zhang, Qing, Xie, Xin, Nan, Fa-Jun

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 2.54 MB

2020

3

Synthesis and biological evaluation of novel bisheterocycle-containing compounds as potential anti-influenza virus agents

Wen-Long Wang, De-Yong Yao, Min Gu, Min-Zhi Fan, Jing-Ya Li, Ya-Cheng Xing, Fa-Jun Nan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 189 KB

english, 2005

4

Effect of a hepatitis B virus inhibitor, NZ-4, on capsid formation

Yang, Li, Wang, Ya-Juan, Chen, Hai-Jun, Shi, Li-Ping, Tong, Xian-Kun, Zhang, Yang-Ming, Wang, Gui-Feng, Wang, Wen-Long, Feng, Chun-Lan, He, Pei-Lan, Xu, Yi-Bin, Lu, Meng-Ji, Tang, Wei, Nan, Fa-Jun, Zu

Journal:

Antiviral Research

Year:

2016

Language:

english

File:

PDF, 1.81 MB

english, 2016

5

Design, Synthesis, and Biological Evaluation of Caprolactam-Modified Bengamide Analogues

Gang Liu, Yi-Ming Ma, Wan-Yi Tai, Chuan-Ming Xie, Yu-Lin Li, Jia Li, Fa-Jun Nan

Journal:

Year:

2008

Language:

english

File:

PDF, 222 KB

english, 2008

6

Inhibition of KCNQ2/3 channels by HN38 and XE991 depends on the conformation of the outer vestibule

Rodier, Elizabeth, Niday, Zachary, Doci, Klarita, Wang, Lei, Nan, Fa-Jun, Gao, Zhao-Bing, Tzingounis, Anastasios V

Journal:

Molecular Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.13 MB

english, 2018

7

Design, synthesis, and biological evaluation of novel 2-ethyl-5-phenylthiazole-4-carboxamide derivatives as protein tyrosine phosphatase 1B inhibitors with improved cellular efficacy

Chen, Yue-Ting, Tang, Chun-Lan, Ma, Wei-Ping, Gao, Li-Xin, Wei, Yi, Zhang, Wei, Li, Jing-Ya, Li, Jia, Nan, Fa-Jun

Journal:

European Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.26 MB

english, 2013

8

Synthesis and biological evaluation of immunosuppressive agent DZ2002 and its stereoisomers

Yang-Ming Zhang, Yu Ding, Wei Tang, Wei Luo, Min Gu, Wei Lu, Jie Tang, Jian-Ping Zuo, Fa-Jun Nan

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 286 KB

english, 2008

9

Structural analysis of inhibition ofE. colimethionine aminopeptidase: implication of loop adaptability in selective inhibition of bacterial enzymes

Ze-Qiang Ma, Sheng-Xue Xie, Qing-Qing Huang, Fa-Jun Nan, Thomas D Hurley, Qi-Zhuang Ye

Journal:

BMC Structural Biology

Year:

2007

Language:

english

File:

PDF, 4.97 MB

english, 2007

10

RCM-mediated stereoselective synthesis of three novel tetrahydroisoquinoline tetracyclic core frameworks

Qing-Qing Huang, Lin-Hai Chen, Fa-Jun Nan

Journal:

Tetrahedron Letters

Year:

2008

Language:

english

File:

PDF, 182 KB

english, 2008

11

Design, Synthesis, and Biological Evaluation of Isoquinoline-1,3,4-trione Derivatives as Potent Caspase-3 Inhibitors

Chen, Yi-Hua, Zhang, Ya-Hui, Zhang, Hua-Jie, Liu, Da-Zhi, Gu, Min, Li, Jing-Ya, Wu, Fang, Zhu, Xing-Zu, Li, Jia, Nan, Fa-Jun

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 289 KB

english, 2006

12

Discovery of aryl sulfonamide-selective Nav1.7 inhibitors with a highly hydrophobic ethanoanthracene core

Wang, Jin-tao, Zheng, Yue-ming, Chen, Yue-ting, Gu, Min, Gao, Zhao-bing, Nan, Fa-jun

Journal:

Acta Pharmacologica Sinica

Year:

2019

File:

PDF, 1.92 MB

2019

13

Synthetic studies towards Chlorahololides A: practical synthesis of a lindenane-type sesquiterpenoid core framework with a 5,6-double bond

Yong Liu, Fa-Jun Nan

Journal:

Tetrahedron Letters

Year:

2010

Language:

english

File:

PDF, 303 KB

english, 2010

14

Discovery and Structural Modification of 1-Phenyl-3-(1-phenylethyl)urea Derivatives as Inhibitors of Complement

Zhang, Mei, Yang, Xiao-Ying, Tang, Wei, Groeneveld, Tom W. L., He, Pei-Lan, Zhu, Feng-Hua, Li, Jia, Lu, Wei, Blom, Anna M., Zuo, Jian-Ping, Nan, Fa-Jun

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 564 KB

english, 2012

15

Sulfuretin protects hepatic cells through regulation of ROS levels and autophagic flux

Lu, Yu-Ting, Xiao, Yu-Feng, Li, Yu-Feng, Li, Jia, Nan, Fa-Jun, Li, Jing-Ya

Journal:

Acta Pharmacologica Sinica

Year:

2018

Language:

english

File:

PDF, 2.62 MB

english, 2018

16

Isoquinoline-1,3,4-trione and its derivatives attenuate β-amyloid-induced apoptosis of neuronal cells

Ya-Hui Zhang, Hua-Jie Zhang, Fang Wu, Yi-Hua Chen, Xue-Qin Ma, Jun-Qin Du, Zhong-Liang Zhou, Jing-Ya Li, Fa-Jun Nan, Jia Li

Journal:

Year:

2006

Language:

english

File:

PDF, 533 KB

english, 2006

17

Periplocoside A, a pregnane glycoside from Periploca sepium Bge, prevents concanavalin A-induced mice hepatitis through inhibiting NKT-derived inflammatory cytokine productions

Jin Wan, Yi-Na Zhu, Jia-Quan Feng, Hai-Jun Chen, Ru-Jun Zhang, Jia Ni, Zhen-Hua Chen, Li-Fei Hou, Quan-Fang Liu, Jing Zhang, Li Yang, Wei Tang, Yi-Fu Yang, Fa-Jun Nan, Wei-Ming Zhao, Jian-Ping Zuo

Journal:

International Immunopharmacology

Year:

2008

Language:

english

File:

PDF, 1012 KB

english, 2008

18

AMPK Activators as Novel Therapeutics for Type 2 Diabetes

Yu, Li-Fang, Qiu, Bei-Ying, Nan, Fa-Jun, Li, Jia

Journal:

Current Topics in Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 418 KB

english, 2010

19

Inhibitors of type I MetAPs containing pyridine-2-carboxylic acid thiazol-2-ylamide. Part 1: SAR studies on the determination of the key scaffold

Qun-Li Luo, Jing-Ya Li, Zhi-Ying Liu, Ling-Ling Chen, Jia Li, Qi-Zhuang Ye, Fa-Jun Nan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 134 KB

english, 2005

20

Identification of potent type I MetAP inhibitors by simple bioisosteric replacement. Part 1: Synthesis and preliminary SAR studies of thiazole-4-carboxylic acid thiazol-2-ylamide derivatives

Yong-Mei Cui, Qing-Qing Huang, Jie Xu, Ling-Ling Chen, Jing-Ya Li, Qi-Zhuang Ye, Jia Li, Fa-Jun Nan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 276 KB

english, 2005

21

Metalloform-selective inhibition: Synthesis and structure–activity analysis of Mn(II)-form-selective inhibitors of Escherichia coli methionine aminopeptidase

Qing-Qing Huang, Min Huang, Fa-Jun Nan, Qi-Zhuang Ye

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 194 KB

english, 2005

22

Design, synthesis and biological evaluation of bisthiazole-based trifluoromethyl ketone derivatives as Potent HDAC inhibitors with improved cellular efficacy

Gong, Chao-Jun, Gao, An-Hui, Zhang, Yang-Ming, Su, Ming-Bo, Chen, Fei, Sheng, Li, Zhou, Yu-Bo, Li, Jing-Ya, Li, Jia, Nan, Fa-Jun

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 666 KB

english, 2016

23

Inhibitors of type I MetAPs containing pyridine-2-carboxylic acid thiazol-2-ylamide. Part 2: SAR studies on the pyridine ring 3-substituent

Qun-Li Luo, Jing-Ya Li, Ling-Ling Chen, Jia Li, Qi-Zhuang Ye, Fa-Jun Nan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 293 KB

english, 2005

24

Total Synthesis of the Originally Proposed and Revised Structures of Scleritodermin A

Liu, Sheng, Cui, Yong-Mei, Nan, Fa-Jun

Journal:

Organic Letters

Year:

2008

Language:

english

File:

PDF, 139 KB

english, 2008

25

Synthesis and Antiviral Activity of Conformational Analogues of Leucamide A

Wang, Wen-Long, Chen, Hai-Jun, Ma, Wei-Ping, Gu, Min, Fan, Min-Zhi, Li, Jing-Ya, Feng, Bainian, Nan, Fa-Jun

Journal:

Year:

2012

Language:

english

File:

PDF, 299 KB

english, 2012

26

Synthesis and in vitro and in vivo biological evaluation of tissue-specific bisthiazole Histone deacetylase (HDAC) inhibitors

Zhang, Shu-Wei, Gong, Chao-Jun, Su, Ming-Bo, Chen, Fei, He, Ting, Zhang, Yang-Ming, Shen, Qian-Qian, Su, Yi, Ding, Jian, Li, Jia, Chen, Yi, Nan, Fa-Jun

Journal:

Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 1.14 MB

english, 2019

27

An Efficient Synthesis of 2-Chloropyrimidines via Pd-catalyzed Regioselective Dechlorination of 2,4-Dichloropyrimidines in the Presence of NaHCO3

Yang-Ming ZHANG, Min GU, Hui MA, Jie TANG, Wei LU, Fa-Jun NAN

Journal:

Chinese Journal of Chemistry

Year:

2008

Language:

english

File:

PDF, 52 KB

english, 2008

28

Discovery and structural optimization of pyrazole derivatives as novel inhibitors of Cdc25B

Hai-Jun Chen, Yong Liu, Li-Na Wang, Qiang Shen, Jia Li, Fa-Jun Nan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 445 KB

english, 2010

29

Novel irreversible caspase-1 inhibitor attenuates the maturation of intracellular interleukin-1 β

Ma, Xue-Qin, Zhang, Hua-Jie, Zhang, Ya-Hui, Chen, Yi-Hua, Wu, Fang, Du, Jun-Qing, Yu, Hai-Ping, Zhou, Zhong-Liang, Li, Jing-Ya, Nan, Fa-Jun, Li, Jia

Journal:

Biochemistry and Cell Biology

Year:

2007

Language:

english

File:

PDF, 248 KB

english, 2007

30

Novel substituted pyrazolone derivatives as AMP-activated protein kinase activators to inhibit lipid synthesis and reduce lipid accumulation in ob/ob mice

Zhang, Mei, Xie, Zhi-fu, Zhang, Run-tao, Chen, Da-kai, Gu, Min, Cui, Shi-chao, Zhang, Yang-ming, Zhang, Xin-wen, Yu, Yan-yan, Li, Jia, Nan, Fa-jun, Li, Jing-ya

Journal:

Acta Pharmacologica Sinica

Year:

2018

Language:

english

File:

PDF, 1.61 MB

english, 2018

31

Pyrazolone derivative C29 protects against HFD-induced obesity in mice via activation of AMPK in adipose tissue

Li, Bo-han, Zhang, Mei, Duan, Ya-nan, Shuai, Lin, Jiang, Hao-wen, Li, Jia, Nan, Fa-jun, Li, Jing-ya

Journal:

Acta Pharmacologica Sinica

Year:

2020

File:

PDF, 3.69 MB

2020

32

Rational Design and Synthesis of 2,2-Bisheterocycle Tandem Derivatives as Non-Nucleoside Hepatitis B Virus Inhibitors

Hai-Jun Chen, Wen-Long Wang, Gui-Feng Wang, Li-Ping Shi, Min Gu, Yu-Dan Ren, Li-Fei Hou, Pei-Lan He, Feng-Hua Zhu, Xian-Gen Zhong, Wei Tang, Jian-Ping Zuo, Fa-Jun Nan

Journal:

Year:

2008

Language:

english

File:

PDF, 308 KB

english, 2008

33

Synthesis and in vitro and in vivo biological evaluation of tissue-specific bisthiazole Histone deacetylase (HDAC) inhibitors

Zhang, Shu-Wei, Gong, Chao-Jun, Su, Ming-Bo, Chen, Fei, He, Ting, Zhang, Yang-Ming, Shen, Qian-Qian, Su, Yi, Ding, Jian, Li, Jia, Chen, Yi, Nan, Fa-Jun

Journal:

Journal of Medicinal Chemistry

Year:

2019

File:

PDF, 1.14 MB

2019

34

Synthesis and Biological Evaluation of C7-Demethyl Largazole Analogues

Fei Chen, An-Hui Gao, Jia Li, Fa-Jun Nan

Journal:

Year:

2009

Language:

english

File:

PDF, 57 KB

english, 2009

35

Azoxystrobin, a mitochondrial complex III Qo site inhibitor, exerts beneficial metabolic effects in vivo and in vitro

Gao, An-Hui, Fu, Yan-Yun, Zhang, Kun-Zhi, Zhang, Mei, Jiang, Hao-Wen, Fan, Li-Xia, Nan, Fa-Jun, Yuan, Chong-Gang, Li, Jia, Zhou, Yu-Bo, Li, Jing-Ya

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2014

Language:

english

File:

PDF, 1.73 MB

english, 2014

36

Discovery of a novel calcium-sensitive fluorescent probe for α-ketoglutarate

Gan, Lin-lin, Chen, Lin-hai, Nan, Fa-jun

Journal:

Acta Pharmacologica Sinica

Year:

2017

Language:

english

File:

PDF, 1.99 MB

english, 2017

37

Design and synthesis of biotin-tagged photoaffinity probes of jasmonates

Min Gu, Jianbin Yan, Zhiyan Bai, Yue-Ting Chen, Wei Lu, Jie Tang, Liusheng Duan, Daoxin Xie, Fa-Jun Nan

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 699 KB

english, 2010

38

Specificity for inhibitors of metal-substituted methionine aminopeptidase

Jing-Ya Li, Ling-Ling Chen, Yong-Mei Cui, Qun-Li Luo, Jia Li, Fa-Jun Nan, Qi-Zhuang Ye

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 218 KB

english, 2003

39

Discovery of a Negative Allosteric Modulator of GABA B Receptors

Chen, Lin-Hai, Sun, Bing, Zhang, Yang, Xu, Tong-Jie, Xia, Zhi-Xiong, Liu, Jian-Feng, Nan, Fa-Jun

Journal:

ACS Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 888 KB

english, 2014

40

Discovery of 3-substituted 1H-indole-2-carboxylic Acid De-rivatives as a Novel Class of CysLT1 Selective Antagonists

Chen, Hua-Yan, Yang, Hui, Wang, Zhi-Long, Xie, Xin, Nan, Fa-Jun

Journal:

ACS Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 558 KB

english, 2016

41

ChemInform Abstract: Synthetic Studies Towards Chlorahololides A: Practical Synthesis of a Lindenane-Type Sesquiterpenoid Core Framework with a 5,6-Double Bond.

Yong Liu, Fa-Jun Nan

Journal:

Year:

2010

File:

PDF, 29 KB

2010

42

A facile semisynthesis of 2′,7-bisacetyltaxol from 10-DABa

Min Gu,Yang-Ming Zhang,Wei Luo,Wei Lu,Fa-Jun Nan

Journal:

Chemistry of Natural Compounds

Year:

2012

Language:

english

File:

PDF, 55 KB

english, 2012

43

Development of Novel Alkene Oxindole Derivatives As Orally Efficacious AMP-Activated Protein Kinase Activators

Yu, Li-Fang, Li, Yuan-Yuan, Su, Ming-Bo, Zhang, Mei, Zhang, Wei, Zhang, Li-Na, Pang, Tao, Zhang, Run-Tao, Liu, Bing, Li, Jing-Ya, Li, Jia, Nan, Fa-Jun

Journal:

ACS Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 1014 KB

english, 2013

44

Novel KCNQ2 channel activators discovered using fluorescence-based and automated patch-clamp-based high-throughput screening techniques

Yue, Jin-feng, Qiao, Guan-hua, Liu, Ni, Nan, Fa-jun, Gao, Zhao-bing

Journal:

Acta Pharmacologica Sinica

Year:

2016

Language:

english

File:

PDF, 958 KB

english, 2016

45

Design and synthesis of simple, yet potent and selective non-ring-A pyripyropene A-based inhibitors of acyl-coenzyme A: cholesterol acyltransferase 2 (ACAT2)

Zhan, Yang, Zhang, Xiao-Wei, Xiong, Ying, Li, Bo-Liang, Nan, Fa-Jun

Journal:

Organic & Biomolecular Chemistry

Year:

2016

Language:

english

File:

PDF, 537 KB

english, 2016

46

Complexes of the Malonyl Dihydrazone of Salicylaldehyde with Lanthanides

Huang Guo-Sheng, Liang Yong-Min, Nan Fa-Jun, Ma Yong-Xiang

Journal:

Bulletin des Sociétés Chimiques Belges

Year:

1993

Language:

english

File:

PDF, 79 KB

english, 1993

47

Design and synthesis of chromogenic thiopeptolide substrates as MetAPs active site probes

Yong-Mei Cui, Jing-Ya Li, Ling-Ling Chen, Jia Li, Qi-Zhuang Ye, Fa-Jun Nan

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 326 KB

english, 2004

48

Synthesis and biological evaluation of (±)-3-(2-(2-fluorobenzyloxy) naphthalen-6-yl)-2-aminopropanoic acid derivatives as novel PTP1B inhibitors

Liang-Peng Sun, Qiang Shen, Hong-Hua Piao, Wei-Ping Ma, Li-Xin Gao, Wei Zhang, Fa-Jun Nan, Jia Li, Hu-Ri Piao

Journal:

European Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 771 KB

english, 2011

49

Berberine derivatives with a long alkyl chain branched by hydroxyl group and methoxycarbonyl group at 9-position show improved anti-proliferation activity and membrane permeability in A549 cells

Liu, Yi, Zhu, Ke-xin, Cao, Lei, Xie, Zhi-fu, Gu, Min, Lü, Wei, Li, Jing-ya, Nan, Fa-jun

Journal:

Acta Pharmacologica Sinica

Year:

2020

File:

PDF, 3.16 MB

2020

50

Oblongifolinol, a new long chain diol from bark of Litsea rotundifolia var. oblongifolia

Zhao, Ya, Zhang, Wen, Chen, Yi-Hua, Nan, Fa-Jun, Guo, Yue-Wei

Journal:

Natural Product Research

Year:

2006

Language:

english

File:

PDF, 127 KB

english, 2006

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